The 15-day operation from July 21 to Aug. 4 will see police collaborating with 14 enforcement and other agencies.
Police have identified 20 hotspots in the State where enforcement personnel would be deployed.
State Police Commissioner Datuk Jalaluddin Abdul Rahman said the campaign would focus on ensuring smooth traffic flow which is safe and free from accidents for those returning to their hometowns for the holiday.
Also present were Deputy Police Commissioner Datuk Malek Harun and State Police Administration Department Head Datuk Noor Azam Jamaluddin.
"The campaign will not only focus on road safety awareness but also on our waters and on safety measures to be taken to prevent break-ins," he said, after launching the State-level Ops Selamat here.
Jalaluddin advised those going back to their hometowns to inform police of their absence during the holidays by filling in the forms prepared for that purpose.
"They can download the form via our police portal or they can go to the nearest police station and obtain the form before handing it over to our personnel," he said.
"I understand that there are those in the villages who are not able to download the forms via the Internet, which is why I have prepared the necessary form and have ordered all my district police chiefs to conduct a campaign and distribute the forms.
"I will make sure that those who have filled in the form and submit it to us, we will do our level best to make sure there is zero crime," he said, adding that in the three contingents he served, the houses registered with the police achieved zero crime.
On another note, he said, the nationwide Ops Selamat 2012 recorded a total of 17, 930 road accidents with a total of 243 deaths, while Ops Selamat 2013 recorded 17, 830 road accidents with 280 deaths.
"For Sabah, Ops Selamat 2012 recorded a total of 710 road accidents and nine deaths, while Ops Selamat 2013 recorded a total of 734 road accidents and 13 deaths," he said.
"These statistics show an increase but I hope every quarter will work together to reduce the fatality statistic this festive season," he added.